Join us as we learn from Dr. Erika Holzbaur about the important role that DYNC1H1-encoded proteins called Dynein play in brain cells. Dynein dysfunction is a cause of the variety of symptoms that show up in those who have DYNC1H1- Associated Neurological Disorders.
Dr. Erika Holzbaur is a professor at the Perelman School of Medicine at the University of Pennsylvania. Her laboratory is dedicated to the research of motor proteins and their role in various neurodegenerative diseases. Her lab studies “mechanisms of force production and motor function, mechanisms of cargo coupling and regulation, effects of dynein and dynactin on dynamics of the cytoskeleton, and the analysis of neurodegenerative diseases resulting from impairments in dynein/dynactin function. Disruptions in dynein/dynactin function cause motor neuron degeneration and muscle atrophy, leading to motor neuron diseases similar to ALS.” Dr. Erika Holzbaur is a member of the DYNC1H1 Association Scientific Advisory Board, and we are delighted to have her speak.